Resident Evil 6 is the 6th episode of the famous video game which was developed and distributed by the Capcom company. It is not possible to pause a game when playing online where players can enter and exit the game at any time. To be able to pause the Resident Evil game to do something, you must start a game without being logged in. Don't worry, it's very easy to do.
Steps
Part 1 of 3: Getting started

Step 1. Launch the game
Start by launching the Resident Evil game.
- With a PC: double-click on the Resident Evil 6 game icon. This icon represents the 6 on the game cover. You will then see the game's welcome screen.
- With a PS3 and an Xbox 360: launch the game Resident Evil by placing the disc in the drive of your console. Then launch the game from the home page displayed on the screen.

Step 2. Go to the main menu
Click on the welcome screen button that will take you to the main game menu.

Step 3. Select the game mode
Go to the game mode selection page by clicking on play. You now have the option to play in single player or co-op mode. You will then be redirected to the choice of campaign type.
Part 2 of 3: Play offline

Step 1. Choose a character
In the campaign menu, select the character you want to play with. After choosing a character, other options will then be available to you.

Step 2. Select the offline mode
Go to the menu network options and press the Dpad to the right to switch to offline game mode.

Step 3. Start playing
Go to the bottom of the screen and click on Play (Start game). The game will start and your character will be at the first checkpoint that will be available to you.
Part 3 of 3: Pause the game

Step 1. Wait for the game to load
When the game loads, you will be able to see your character in third-person mode.

Step 2. Pause the game
If you want to pause the game, all you have to do is press start. The game will then normally be paused and you will be able to use items and choose different options without risk to your character.